|
R21 |
2021 |
|
- Fred Hutchinson Cancer Research Center
|
Predicting transcriptional signatures and tumor subtypes from circulating tumor DNA |
Active |
|
R21 |
2021 |
|
- New York University School Of Medicine
|
Inferring cell state tumor microenvironment maps by integrating single-cell and spatial transcriptomics |
Active |
|
U01 |
2021 |
- Joshua Campbell
- Masanao Yajima
|
- Boston University Medical Campus
|
Utilizing Bayesian modeling to improve mutational signature inference in large-scale datasets |
Active |
|
U01 |
2021 |
|
|
Advanced development of Lancet, an emerging tool for complex variant calling in cancer genomics |
Active |
|
U01 |
2021 |
|
- UT Southwestern Medical Center
|
Informatics Tools To Analyze And Model Whole Slide Image Data At The Single Cell Level |
Active |
|
U01 |
2021 |
|
|
An informatics bridge over the valley of death for cancer Phase I trials of drug-combination therapies |
Active |
|
R21 |
2021 |
|
|
Extraction of Symptom Burden from Clinical Narratives of Cancer Patients using Natural Language Processing |
Active |
|
U24 |
2021 |
- Christina Yung
- Lincoln D Stein
|
- Ontario Institute For Cancer Research
|
Overture: A Multi-Scale Data Platform for Cancer Genomics Research |
Active |
|
R21 |
2021 |
|
|
Optimizing the Population Representativeness of Older Adults in Cancer Trials |
Active |
|
U24 |
2021 |
|
- University Of California, San Diego
|
Software and algorithms for elucidating the structure, function, and evolution of extrachromosomal DNA |
Active |
|
U24 |
2021 |
- ALESSANDRO SETTE
- BJOERN PETERS
|
- LA JOLLA INSTITUTE FOR IMMUNOLOGY
|
THE CANCER EPITOPE DATABASE AND ANALYSIS RESOURCE |
Active |
|
U24 |
2021 |
- Jill Mesirov
- James Thomas Robinson
|
- University Of California, San Diego
|
The Integrative Genomics Viewer (IGV) for Cancer Research |
Active |
|
U24 |
2021 |
|
|
Sustaining the Integrative Imaging Informatics for Cancer Research (I3CR) Center |
Active |
|
U01 |
2021 |
|
|
Integrative genomic and epigenomic analysis of cancer using long read sequencing |
Active |
|
U01 |
2021 |
- LYDIA E KAVRAKI
- GREGORY A LIZEE
|
|
PROTEAN-CR: Proteomics Toolkit for Ensemble Analysis in Cancer Research |
Active |
|
U24 |
2021 |
- Jingchun Zhu
- David H Haussler
|
- University of California Santa Cruz
|
Enhance UCSC Xena: extend interactive visualization to ultra-large-scale multi-omics data and integrate with analysis resources |
Active |
|
R21 |
2021 |
|
|
Curve-free phase I/II clinical trial designs for molecularly targeted agents and immunotherapy |
Active |
|
R21 |
2021 |
|
- University Of California, San Francisco
|
Computational approaches to unravel immune receptor sequencing for cancer immunotherapy |
Active |
|
R21 |
2021 |
|
- University Of South Carolina At Columbia
|
scDECO: A novel statistical framework to identify differential co-expression gene combinations systematically using single-cell RNA sequencing data |
Active |
|
R01 |
2020 |
|
- Beckman Research Institute/City of Hope
|
Integrative Analyses of Saturation CRISPR Protein Scan |
Active |
|
U24 |
2020 |
- Kooresh Isaac Shoghi
- Daniel Scott Marcus
|
|
Development of an Open-Source Preclinical Imaging Informatics Platform for Cancer Research |
Active |
|
UE5 |
2020 |
- Jeffery T Leek
- Jeremy Goecks
- Karriem Sadot Watson
- Sarah J Wheelan
|
- Johns Hopkins University
- Oregon Health & Science University
|
Scalable multi-mode education to increase use of ITCR tools by diverse analysts |
Active |
|
U24 |
2020 |
|
- Northern Arizona University
|
Advancing Our Understanding of Cancer and the Human Microbiome with QIIME 2 |
Active |
|
U24 |
2020 |
|
|
Comprehensive and Robust Tools for Analysis of Tumor Heterogeneity and Evolution |
Active |
|
U01 |
2020 |
- Satish Viswanath
- Pallavi Tiwari
|
- Case Western Reserve University
|
RadxTools for Assessing Tumor Treatment Response on Imaging |
Active |
|
U24 |
2020 |
- Guergana K Savova
- Harry S Hochheiser
- Jeremy Lyle Warner
|
- Boston Children's Hospital
- University of Pittsburgh at Pittsburgh
- Vanderbilt University Medical Center
|
Cancer Deep Phenotype Extraction from Electronic Medical Records |
Active |
|
U24 |
2020 |
- James Eddy
- Paul Christopher Boutros
|
- Sage Bionetworks
- University of California Los Angeles
|
Advancing Method Benchmarking and Data Sharing Through Crowd-Sourced Competitions in Cancer Research |
Active |
|
R21 |
2020 |
|
- Rutgers Cancer Institute of New Jersey
|
Inference of Tumor Growth Dynamics Using Genomic Data |
Active |
|
U24 |
2020 |
- Jill Mesirov
- Pablo Tamayo
|
- University of California, San Diego
|
GenePattern and GenePattern Notebook: Integrative 'Omic Analysis for Cancer Research |
Active |
|
U01 |
2020 |
|
- Washington University in St. Louis
|
Informatics Tools for Identification, Prioritization, and Clinical Application of Neoantigens |
Active |
|
R21 |
2020 |
|
- Massachusetts General Hospital
|
A Computational Method to Calculate the Radiation Dose to Circulating Lymphocytes |
Active |
|
U01 |
2020 |
|
|
Single-cell and imaging data integration software to spatially resolve the tumor microenvironment |
Active |
|
U24 |
2020 |
- Jesse Samuel Bohem
- Aviad Tsherniak
|
|
Advanced development of the Cancer Dependency Map portal (DepMap.org) |
Active |
|
U01 |
2020 |
|
- UNIVERSITY OF TX MD ANDERSON CAN CTR
|
Informatics for Functional Integration of Heterogeneous Cancer Genome and Transcriptome Sequencing Data |
Active |
|
U24 |
2020 |
- Helen Elizabeth Parkinson
- Terrence Meehan
|
- European Molecular Biology Laboratory
|
Patient Derived Cancer Model (PDCM) Finder |
Active |
|
U01 |
2020 |
|
|
Technology for efficient simulation of cancer cell transport |
Active |
|
R21 |
2020 |
- Jennifer Ellen Beane
- Vijaya B Kolachalama
|
- Boston University Medical Campus
|
PRISTINE: Pre-cancer histology identification of Endobronchial biopsies using deep learning |
Active |
|
R21 |
2020 |
|
|
Cancer-specific gene set testing |
Active |
|
U01 |
2019 |
|
- University of California, Santa Cruz
|
Eliminating Variants of Uncertain Significance in BRCA1, BRCA2 and Beyond |
Active |
|
U01 |
2019 |
- Daniel Rubin
- Jayashree Kalpathy-Cramer
|
- Stanford University
- Massachusetts General Hospital
|
Distributed Learning of Deep Learning Models for Cancer Research |
Active |
|
U01 |
2019 |
|
- University of California Los Angeles
|
Informatics Resources for Liquid Biopsy Research |
Active |
|
U24 |
2019 |
|
- Dana-Farber Cancer Institute
|
Developing Informatics Technologies to Model Cancer Gene Regulation |
Active |
|
U01 |
2019 |
- Andrew Janowczyk
- Anant Madabhushi
|
- Case Western Reserve University
|
HistoTools: A Suite of Digital Pathology Tools for Quality Control, Annotation and Dataset Identification |
Active |
|
U24 |
2019 |
|
|
Standardized and Genome-Wide Clinical Interpretation of Complex Genotypes for Cancer Precision Medicine |
Active |
|
U01 |
2019 |
|
- General Electric Global Research Center
|
Open-Access X-Ray and CT Simulation Toolkit for Research in Cancer Imaging and Dosimetry |
Active |
|
U01 |
2019 |
|
- Emory University
- Stony Brook University
|
Computational Pathology Software for Integrative Cancer Research with Three-Dimensional Digital Slides |
Active |
|
U01 |
2019 |
|
- University of Pennsylvania
|
The Federated Tumor Segmentation (FeTS) Platform: An Intuitive Tool Facilitating Secure Multi-Institutional Collaboration |
Active |
|
U24 |
2019 |
|
- Harvard School of Public Health
|
WebMeV: A Robust Platform for Intuitive Genomic Data Analysis |
Active |
|
U24 |
2018 |
|
|
Detection of somatic, subclonal and mosaic CNVs from sequencing |
Active |
|
U24 |
2018 |
|
- University of California, San Francisco
|
The TOPAS Tool for Particle Simulation, a Monte Carlo Simulation Tool for Physics, Biology and Clinical Research |
Active |
|
U01 |
2018 |
- Lee Cooper
- Christopher Flowers
- Metin Gurcan
|
- Emory University
- Ohio State University
|
Informatics Tools for Quantitative Digital Pathology Profiling and Integrated Prognostic Modeling |
Active |
|
U24 |
2018 |
|
- University of California, San Diego
|
Supporting and Evolving Gene Set Enrichment Analysis and the Molecular Signatures Database for Cancer Research |
Active |
|
U24 |
2018 |
- Jeremy Goecks
- James Taylor
|
- Oregon Health and Science University
- Johns Hopkins University
|
A Federated Galaxy for user-friendly large-scale cancer genomics research |
Active |
|
U24 |
2017 |
- Guilherme Del Fiol
- Kensaku Kawamoto
|
|
Scalable Clinical Decision Support for Individualized Cancer Risk Management |
Active |
|
U24 |
2017 |
|
|
Building Protected Data Sharing Networks to Advance Cancer Risk Assessment and Treatment |
Active |
|
U24 |
2017 |
- Nikolaus Schultz
- Ethan Cerami
- Chris Sander
|
- Sloan Kettering Institute for Cancer Research
|
The cBioPortal for Cancer Genomics |
Active |
|
U24 |
2017 |
|
|
Advanced Development and Dissemination of EMERSE for Cancer Phenotyping from Medical Records |
Active |
|
U24 |
2017 |
- Fred Prior
- Joel Saltz
- Ashish Sharma
|
- University of Arkansas
- Stony Brook University
- Emory University
|
TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision Medicine |
Active |
|
U24 |
2014 |
|
- University of California, San Diego
|
NDEx - the Network Data Exchange, A Network Commons for Biologists |
Active |
|
U24 |
2014 |
|
- Roswell Park Cancer Institute
|
Cancer Genomics: Integrative and Scalable Solutions in R / Bioconductor |
Active |
|
U24 |
2013 |
|
|
Trinity: Transcriptome Assembly for Genetic and Functional Analysis of Cancer |
Active |
|
R21 |
2019 |
|
- Boston University Medical Campus
|
Enhanced Deconvolution and Prediction of Mutational Signatures |
Complete |
|
R21 |
2019 |
|
- University of Southern California
|
Conservation and Functional-Characterization of Tumor Methylation Sites |
Complete |
|
R21 |
2019 |
|
- University of California at Davis
|
Personalized Dosimetry for Liver Cancer Radioembolization Using Fluid Dynamics Simulation |
Complete |
|
R21 |
2019 |
|
- University of Colorado Denver
|
Development and Dissemination of KiNet: A Novel Imaging Informatics Tool for Gastrointestinal and Pancreatic Neuroendocrine Tumors |
Complete |
|
R21 |
2019 |
- Jin Chen
- Guo-Qiang Zhang
- Baowei Fei
|
- University of Kentucky
- The University Texas at Dallas
|
STAN-CT: Standardization and Normalization of CT images for Lung Cancer Patients |
Complete |
|
R21 |
2019 |
|
- Dana-Farber Cancer Institute
|
A Statistical Framework to Systematically Characterize Cancer Driver Mutations in Noncoding Genomic Regions |
Complete |
|
R21 |
2019 |
|
|
Semi-supervised Algorithms for Risk Assessment with Noisy EHR Data |
Complete |
|
R21 |
2019 |
- Suvra Pal
- Leili Shahriyari
- Souvik Roy
|
- University of Texas Arlington
- University of Massachusetts Amherst
|
Data-Driven QSP Software for Personalized Colon Cancer Treatment |
Complete |
|
U01 |
2018 |
|
- Dana-Farber Cancer Institute
|
Bioinformatics Technology to Characterize Tumor Infiltrating Immune Repertoires |
Complete |
|
U01 |
2018 |
- Linda Shapiro
- Joann Elmore
|
|
A Unified Machine Learning Package for Cancer Diagnosis |
Complete |
|
U01 |
2018 |
|
- Children's Hospital of Philadelphia
|
Tools for annotating mutations in the 3D cancer genome |
Complete |
|
R21 |
2018 |
- Min Jin Ha
- Veerabhadran Baladandayuthapani
|
- University of Texas MD Anderson Cancer Center
- University of Michigan
|
Proteomic-based integrated subject-specific networks in cancer |
Complete |
|
R21 |
2018 |
|
- University of California, Los Angeles
|
Predicting the Presence of Clinically Significant Prostate Cancer using Multiparametric MRI and MR-US Fusion Biopsy |
Complete |
|
R21 |
2018 |
- Guo-Qiang Zhang
- Licong Cui
|
- University of Kentucky Research Foundation
- University of Kentucky Research Foundation
|
An Ontology-driven Faceted Query Engine for the Kentucky Cancer Registry |
Complete |
|
R21 |
2018 |
|
|
Inferring Kinase Activity Profiles from Phosphoproteomic Data |
Complete |
|
R21 |
2018 |
|
- Sloan Kettering Institute for Cancer Research
|
Statistical Evaluation and Selection of Normalization Methods for microRNA Sequencing Data in Cancer Biomarker Studies |
Complete |
|
U01 |
2018 |
|
- Vanderbilt University Medical Center
|
Network Analysis for a Data-Driven Approach to Cancer Care |
Complete |
|
R21 |
2018 |
|
|
Somatic variant calling and phasing using colored de Bruijn graphs in heterogeneous tumors |
Complete |
|
R21 |
2018 |
|
- Medical College of Wisconsin
|
Bayesian learning algorithms for identifying and classifying heterogeneity of cell types in variety of solid tumors |
Complete |
|
U24 |
2017 |
|
- University of California, Berkeley
- Ontario Institute for Cancer Research
|
Developing the JBrowse Genome Browser to Visualize Structural Variants and Cancer Genomics Data |
Complete |
|
U01 |
2017 |
|
|
An interactive analysis toolkit for single cell RNA-seq in cancer research |
Complete |
|
R21 |
2017 |
|
- Brigham and Women's Hospital
|
Integrative Genomic Framework for Dissecting Regulatory Mechanisms Underlying Hepatocellular Carcinoma |
Complete |
|
Contract |
2017 |
- Timothy Olsen
- Daniel Marcus
|
- Radiologic, Inc.
- Washington University in St. Louis
|
FDA Compliant Imaging Informatics for Cancer Research |
Complete |
|
Contract |
2017 |
- Trinity Urban
- Gordon Harris
|
- Precision Imaging Metrics
- Harvard Medical School
|
Cloud-Hosted Clinical Trial Imaging Assessment and Workflow Management System |
Complete |
|
R21 |
2017 |
|
- Icahn School of Medicine at Mount Sinai
|
A network-based approach for personalized treatment of Multiple Myeloma |
Complete |
|
R21 |
2017 |
|
|
CGDnet: Cancer Gene Drug Network: Using patient-specific drug-gene networks for recommending targeted cancer therapies |
Complete |
|
U01 |
2017 |
|
- Brigham and Women's Hospital
|
Accelerating Cancer Genomics with Cloud-Scale Bioconductor |
Complete |
|
U01 |
2017 |
- Daniel Crichton
- Raja Mazumder
|
- Jet Propulsion Laboratory
- George Washington University
|
Integration of Comprehensive Cancer Mutation and Expression-Associated Data for Biomarker Evaluation and Discovery |
Complete |
|
R01 |
2017 |
|
- University of Illinois at Chicago
- Wayne State University
|
Database and Tools for Functional Inference and Mechanistic Insight into Somatic Cancer Mutations |
Complete |
|
U01 |
2016 |
|
- University of California, Los Angeles
|
Informatics Tools for Single-Nucleotide Analysis of Cancer RNA-Seq |
Complete |
|
U24 |
2016 |
|
- University of Texas MD Anderson Cancer Center
|
The Cancer Proteome Atlas, TCPA: An Integrated Bioinformatics Resource for Functional Cancer Proteomic Data |
Complete |
|
U24 |
2016 |
|
|
A Galaxy-Based Multi-Omic Informatics Hub for Cancer Researchers |
Complete |
|
U24 |
2016 |
- Daniel Marcus
- Richard Wahl
|
- Washington University in St. Louis
|
Integrative Imaging Informatics for Cancer Research |
Complete |
|
U24 |
2016 |
|
- European Molecular Biology Laboratory
|
The PDX Integrator - Re-Purposing KOMP2 Informatics to Widely Disseminate Data from Patient Derived Xenografts |
Complete |
|
U24 |
2016 |
|
|
Informatics Tools for High-Throughput Analysis of Cancer Mutations |
Complete |
|
R21 |
2016 |
|
|
Developing Enabling PET-CT Image Analysis Tools for Predicting Response in Radiation Cancer Therapy |
Complete |
|
R21 |
2016 |
- Lydia Kavraki
- Gregory Lizee
|
|
Structure-Based Selection of Tumor-Antigens for T-Cell Based Immunotherapy |
Complete |
|
R21 |
2016 |
- Dongjun Chung
- Linda Kelemen
|
- Medical University of South Carolina
|
Algorithms for Literature-Guided Multi-Platform Identification of Cancer Subtypes |
Complete |
|
U24 |
2016 |
- Hua Xu
- Jeremy Warner
- Ping Yang
|
- University of Texas Health Sci. Center, Houston
- Vanderbilt University
- Mayo Clinic - Jacksonville, Florida
|
Advancing Cancer Pharmacoepidemiology Research Through EHRs and Informatics |
Complete |
|
U01 |
2016 |
|
- Washington University in St. Louis
|
Development of Informatics Resources for Interpretation of Clinically Actionable Variants in Cancer |
Complete |
|
U24 |
2016 |
|
- University of California, San Diego
|
The Integrative Genomics Viewer (IGV): Visualization Supporting Cancer Research |
Complete |
|
U01 |
2016 |
- Srinivas Chakra Chennubhotla
- Daryl Sarachan
- Lansing Taylor
|
|
Informatics Tools for Tumor Heterogeneity in Multiplexed Fluorescence Images |
Complete |
|
U24 |
2016 |
- Gabor Marth
- Aaron Quinlan
|
|
Monitoring Tumor Subclonal Heterogeneity Over Time and Space |
Complete |
|
U01 |
2015 |
|
|
Open Source Diffusion MRI Technology for Brain Cancer Research |
Complete |
|
U01 |
2015 |
|
|
Informatics Links between Histological Features and Genetics in Cancer |
Complete |
|
U01 |
2015 |
- Michael Wigler
- Alexander Krasnitz
|
- Cold Spring Harbor Laboratory
|
Computational Framework for Single-Cell Genomics of Tumors |
Complete |
|
U24 |
2015 |
- Anant Madabhushi
- Metin Nafi Gurcan
- Anne Martel
|
- Case Western Reserve University
- Ohio State University
- University of Toronto
|
Pathology Image Informatics Platform for Visualization, Analysis and Management |
Complete |
|
U24 |
2015 |
|
|
Extensible Open-Source Zero-Footprint Web Viewer for Oncologic Imaging Research |
Complete |
|
U24 |
2015 |
- Christos Davatzikos
- Despina Kontos
|
- University of Pennsylvania
|
Cancer Imaging Phenomics Software Suite: Application to Brain and Breast Cancer |
Complete |
|
U24 |
2015 |
- John Weinstein
- Bradley Broom
|
- University of Texas MD Anderson Cancer Center
|
Next-Generation Clustered Heat Maps for Fluent, Interactive Exploration of Omic Data |
Complete |
|
U24 |
2015 |
- David Andrew Gutman
- Lee Cooper
|
|
Advanced Development of an Open-source Platform for Web-based Integrative Digital Image Analysis in Cancer |
Complete |
|
U24 |
2015 |
|
- University of California, San Diego
|
GenePattern Notebooks for Cancer Research |
Complete |
|
U24 |
2015 |
- John Quackenbush
- Hugo Aerts
|
- Dana-Farber Cancer Institute
|
Quantitative Radiomics System Decoding the Tumor Phenotype |
Complete |
|
R01 |
2014 |
- Laura Rozek
- Maureen Sartor
|
|
Integrative Epigenomic/Genomic Profiling and Biomarker Discovery in HPV+ and HPV- |
Complete |
|
U01 |
2014 |
|
- Mayo Clinic - Rochester, Minnesota
|
caCDE-QA: A Quality Assurance Platform for Cancer Study Common Data Elements |
Complete |
|
U01 |
2014 |
|
- University of Massachusetts Medical School
|
EMR Adverse Drug Event Detection for Pharmacovigilance |
Complete |
|
U01 |
2014 |
|
- University of South Alabama
|
OmniSearch: A Semantic Search Tool for Discovering MicroRNAs' Critical Roles in Human Cancer |
Complete |
|
U01 |
2014 |
|
- Cedars-Sinai Medical Center
|
Software Tools For Regulatory Analysis of Large Cancer Methylome Datasets |
Complete |
|
U01 |
2014 |
- Bobbie-Jo Mary Webb-Robertson
|
- Pacific Northwest National Laboratory
|
Interactive Informatics Resource for Research-driven Cancer Proteomics |
Complete |
|
U24 |
2014 |
- Bruce Rosen
- Jayashree Kalpathy-Cramer
|
- Massachusetts General Hospital
|
Informatics Tools for Optimized Imaging Biomarkers for Cancer Research & Discovery |
Complete |
|
U24 |
2014 |
|
|
Tools to Analyze Morphology and Spatially Mapped Molecular Data |
Complete |
|
U24 |
2014 |
|
- Boston Children's Hospital
- University of Pittsburgh
|
Cancer Deep Phenotyping Extraction from Electronic Medical Records |
Complete |
|
U24 |
2013 |
|
|
Advanced Development of TIES-Enhancing Access to Tissue for Cancer Research |
Complete |
|
U24 |
2013 |
|
- University of California, Santa Cruz
|
Cloud Based Resource for Data Hosting, Visualization and Analysis Using UCSC Cancer Genomics Browser |
Complete |
|
R01 |
2013 |
|
- University of California, Santa Cruz
|
ESCE: Discovering Molecular Processes |
Complete |
|
U24 |
2013 |
- Ron Kikinis
- Andrey Fedorov
|
- Brigham and Women's Hospital
- Harvard Medical School
|
Quantitative Image Informatics for Cancer Research (QIICR) |
Complete |
|
R01 |
2013 |
|
- Massachusetts General Hospital
|
Cloud-Computer-Aided Diagnostic Imaging Decision Support System |
Complete |
|
R01 |
2013 |
|
|
Interpreting Massive Genomic Data Sets via Summarization |
Complete |
|
U01 |
2013 |
|
- Dana-Farber Cancer Institute
|
Developing Informatics Technologies to Model Cancer |
Complete |
|
U01 |
2013 |
|
|
Informatics Tools for High-Throughput Analysis of Cancer Mutations |
Complete |
|
U01 |
2013 |
- Elmer Bernstam
- Funda Meric-Bernstam
|
- University of Texas MD Anderson Cancer Center
- University of Texas Health Sci. Center, Houston
|
Informatics to Enable Routine Personalized Cancer Therapy |
Complete |
|
U01 |
2011 |
|
- Dana-Farber Cancer Institute
|
MeV: Software for Next Generation Genomic Data Analysis |
Complete |
|
R01 |
2002 |
|
|
Electronic Access to Mouse Tumor Data |
Complete |
