Funded Projects

Displaying 1 - 86 of 86
Award Type Award Year PI Name(s) Institution(s) Project Status
R21 2019
  • Joshua Campbell
  • Boston University Medical Campus
Enhanced Deconvolution and Prediction of Mutational Signatures Active
R21 2019
  • Paul Marjoram
  • University of Southern California
Conservation and Functional-Characterization of Tumor Methylation Sites Active
R21 2019
  • Emilie Roncali
  • University of California at Davis
Personalized Dosimetry for Liver Cancer Radioembolization Using Fluid Dynamics Simulation Active
U24 2019
  • Xiaole Shirley Liu
  • Clifford Meyer
  • Dana-Farber Cancer Institute
Developing Informatics Technologies to Model Cancer Gene Regulation Active
U01 2019
  • Andrew Janowczyk
  • Anant Madabhushi
  • Case Western Reserve University
HistoTools: A Suite of Digital Pathology Tools for Quality Control, Annotation and Dataset Identification Active
R21 2019
  • Fuyong Xing
  • Toby Cornish
  • University of Colorado Denver
Development and Dissemination of KiNet: A Novel Imaging Informatics Tool for Gastrointestinal and Pancreatic Neuroendocrine Tumors Active
U24 2019
  • Obi Griffith
  • Washington University
Standardized and Genome-Wide Clinical Interpretation of Complex Genotypes for Cancer Precision Medicine Active
U01 2019
  • Bruno De Man
  • General Electric Global Research Center
Open-Access X-Ray and CT Simulation Toolkit for Research in Cancer Imaging and Dosimetry Active
U24 2018
  • Jill Mesirov
  • University of California, San Diego
Supporting and Evolving Gene Set Enrichment Analysis and the Molecular Signatures Database for Cancer Research Active
R21 2018
  • Kristen Naegle
  • Washington University
Inferring Kinase Activity Profiles from Phosphoproteomic Data Active
R21 2018
  • Li-Xuan Qin
  • Sloan Kettering Institute for Cancer Research
Statistical Evaluation and Selection of Normalization Methods for microRNA Sequencing Data in Cancer Biomarker Studies Active
U01 2018
  • Jeremy Warner
  • Vanderbilt University Medical Center
Network Analysis for a Data-Driven Approach to Cancer Care Active
U24 2018
  • Jeremy Goecks
  • James Taylor
  • Oregon Health and Science University
  • Johns Hopkins University
A Federated Galaxy for user-friendly large-scale cancer genomics research Active
R21 2018
  • Giuseppe Narzisi
  • New York Genome Center
Somatic variant calling and phasing using colored de Bruijn graphs in heterogeneous tumors Active
R21 2018
  • Anjishnu Banerjee
  • Medical College of Wisconsin
Bayesian learning algorithms for identifying and classifying heterogeneity of cell types in variety of solid tumors Active
U01 2018
  • Xiaole Shirley Liu
  • Dana-Farber Cancer Institute
Bioinformatics Technology to Characterize Tumor Infiltrating Immune Repertoires Active
U01 2018
  • Linda Shapiro
  • Joann Elmore
  • University of Washington
A Unified Machine Learning Package for Cancer Diagnosis Active
U01 2018
  • Kai Tan
  • Children's Hospital of Philadelphia
Tools for annotating mutations in the 3D cancer genome Active
U24 2018
  • Alexej Abyzov
  • Mayo Clinic Rochester
Detection of somatic, subclonal and mosaic CNVs from sequencing Active
U24 2018
  • Bruce Faddegon
  • University of California, San Francisco
The TOPAS Tool for Particle Simulation, a Monte Carlo Simulation Tool for Physics, Biology and Clinical Research Active
U01 2018
  • Lee Cooper
  • Christopher Flowers
  • Metin Gurcan
  • Emory University
  • Ohio State University
Informatics Tools for Quantitative Digital Pathology Profiling and Integrated Prognostic Modeling Active
R21 2018
  • Min Jin Ha
  • Veerabhadran Baladandayuthapani
  • University of Texas MD Anderson Cancer Center
  • University of Michigan
Proteomic-based integrated subject-specific networks in cancer Active
R21 2018
  • Corey W. Arnold
  • University of California, Los Angeles
Predicting the Presence of Clinically Significant Prostate Cancer using Multiparametric MRI and MR-US Fusion Biopsy Active
R21 2018
  • Guo-Qiang Zhang
  • Licong Cui
  • University of Kentucky Research Foundation
  • University of Kentucky Research Foundation
An Ontology-driven Faceted Query Engine for the Kentucky Cancer Registry Active
R21 2017
  • Samir Parekh
  • Icahn School of Medicine at Mount Sinai
A network-based approach for personalized treatment of Multiple Myeloma Active
R21 2017
  • Simina Boca
  • Georgetown University
CGDnet: Cancer Gene Drug Network: Using patient-specific drug-gene networks for recommending targeted cancer therapies Active
U01 2017
  • Vincent Carey
  • Brigham and Women's Hospital
Accelerating Cancer Genomics with Cloud-Scale Bioconductor Active
U24 2017
  • David Hanauer
  • University of Michigan
Advanced Development and Dissemination of EMERSE for Cancer Phenotyping from Medical Records Active
U01 2017
  • Daniel Crichton
  • Raja Mazumder
  • Jet Propulsion Laboratory
  • George Washington University
Integration of Comprehensive Cancer Mutation and Expression-Associated Data for Biomarker Evaluation and Discovery Active
U24 2017
  • Fred Prior
  • Joel Saltz
  • Ashish Sharma
  • University of Arkansas
  • Stony Brook University
  • Emory University
TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision Medicine Active
R01 2017
  • Jie Liang
  • Yan-Yuan Tseng
  • University of Illinois at Chicago
  • Wayne State University
Database and Tools for Functional Inference and Mechanistic Insight into Somatic Cancer Mutations Active
U24 2017
  • Ian Holmes
  • Lincoln Stein
  • University of California, Berkeley
  • Ontario Institute for Cancer Research
Developing the JBrowse Genome Browser to Visualize Structural Variants and Cancer Genomics Data Active
U01 2017
  • William Evan Johnson
  • Boston University
An interactive analysis toolkit for single cell RNA-seq in cancer research Active
U24 2017
  • Guilherme Del Fiol
  • Kensaku Kawamoto
  • University of Utah
Scalable Clinical Decision Support for Individualized Cancer Risk Management Active
Contract 2017
  • Timothy Olsen
  • Daniel Marcus
  • Radiologic, Inc.
  • Washington University in St. Louis
FDA Compliant Imaging Informatics for Cancer Research Complete
R21 2017
  • Nathalie Pochet
  • Brigham and Women's Hospital
Integrative Genomic Framework for Dissecting Regulatory Mechanisms Underlying Hepatocellular Carcinoma Active
U24 2017
  • Ian Foster
  • University of Chicago
Building Protected Data Sharing Networks to Advance Cancer Risk Assessment and Treatment Active
Contract 2017
  • Trinity Urban
  • Gordon Harris
  • Precision Imaging Metrics
  • Harvard Medical School
Cloud-Hosted Clinical Trial Imaging Assessment and Workflow Management System Active
U24 2017
  • Nikolaus Schultz
  • Ethan Cerami
  • Chris Sander
  • Sloan Kettering Institute for Cancer Research
The cBioPortal for Cancer Genomics Active
R21 2016
  • Lydia Kavraki
  • Gregory Lizee
  • Rice University
Structure-Based Selection of Tumor-Antigens for T-Cell Based Immunotherapy Active
R21 2016
  • Dongjun Chung
  • Linda Kelemen
  • Medical University of South Carolina
Algorithms for Literature-Guided Multi-Platform Identification of Cancer Subtypes Active
U24 2016
  • Hua Xu
  • Jeremy Warner
  • Ping Yang
  • University of Texas Health Sci. Center, Houston
  • Vanderbilt University
  • Mayo Clinic - Jacksonville, Florida
Advancing Cancer Pharmacoepidemiology Research Through EHRs and Informatics Active
U01 2016
  • Obi Griffith
  • Washington University in St. Louis
Development of Informatics Resources for Interpretation of Clinically Actionable Variants in Cancer Active
U24 2016
  • Jill Mesirov
  • University of California, San Diego
The Integrative Genomics Viewer (IGV): Visualization Supporting Cancer Research Active
U01 2016
  • Srinivas Chakra Chennubhotla
  • Daryl Sarachan
  • Lansing Taylor
  • University of Pittsburgh
Informatics Tools for Tumor Heterogeneity in Multiplexed Fluorescence Images Active
U24 2016
  • Gabor Marth
  • Aaron Quinlan
  • University of Utah
Monitoring Tumor Subclonal Heterogeneity Over Time and Space Active
U01 2016
  • Xinshu Grace Xiao
  • University of California, Los Angeles
Informatics Tools for Single-Nucleotide Analysis of Cancer RNA-Seq Active
U24 2016
  • Han Liang
  • Gordon Mills
  • University of Texas MD Anderson Cancer Center
The Cancer Proteome Atlas, TCPA: An Integrated Bioinformatics Resource for Functional Cancer Proteomic Data Active
U24 2016
  • Timothy Griffin
  • University of Minnesota
A Galaxy-Based Multi-Omic Informatics Hub for Cancer Researchers Active
U24 2016
  • Daniel Marcus
  • Richard Wahl
  • Washington University in St. Louis
Integrative Imaging Informatics for Cancer Research Active
U24 2016
  • Helen Parkinson
  • European Molecular Biology Laboratory
The PDX Integrator - Re-Purposing KOMP2 Informatics to Widely Disseminate Data from Patient Derived Xenografts Active
U24 2016
  • Rachel Karchin
  • Johns Hopkins University
Informatics Tools for High-Throughput Analysis of Cancer Mutations Active
R21 2016
  • Xiaodong Wu
  • University of Iowa
Developing Enabling PET-CT Image Analysis Tools for Predicting Response in Radiation Cancer Therapy Active
U24 2015
  • Jill Mesirov
  • University of California, San Diego
GenePattern Notebooks for Cancer Research Active
U24 2015
  • John Quackenbush
  • Hugo Aerts
  • Dana-Farber Cancer Institute
Quantitative Radiomics System Decoding the Tumor Phenotype Active
U01 2015
  • Lauren Jean O'Donnell
  • Harvard Medical School
Open Source Diffusion MRI Technology for Brain Cancer Research Active
U01 2015
  • Kun Huang
  • Ohio State University
Informatics Links between Histological Features and Genetics in Cancer Complete
U01 2015
  • Michael Wigler
  • Alexander Krasnitz
  • Cold Spring Harbor Laboratory
Computational Framework for Single-Cell Genomics of Tumors Complete
U24 2015
  • Anant Madabhushi
  • Metin Nafi Gurcan
  • Anne Martel
  • Case Western Reserve University
  • Ohio State University
  • University of Toronto
Pathology Image Informatics Platform for Visualization, Analysis and Management Active
U24 2015
  • Gordon Harris
  • Harvard Medical School
Extensible Open-Source Zero-Footprint Web Viewer for Oncologic Imaging Research Active
U24 2015
  • Christos Davatzikos
  • Despina Kontos
  • University of Pennsylvania
Cancer Imaging Phenomics Software Suite: Application to Brain and Breast Cancer Active
U24 2015
  • John Weinstein
  • Bradley Broom
  • University of Texas MD Anderson Cancer Center
Next-Generation Clustered Heat Maps for Fluent, Interactive Exploration of Omic Data Active
U24 2015
  • David Andrew Gutman
  • Lee Cooper
  • Emory University
Advanced Development of an Open-source Platform for Web-based Integrative Digital Image Analysis in Cancer Active
U24 2014
  • Bruce Rosen
  • Jayashree Kalpathy-Cramer
  • Massachusetts General Hospital
Informatics Tools for Optimized Imaging Biomarkers for Cancer Research & Discovery Active
U24 2014
  • Joel Saltz
  • Stony Brook University
Tools to Analyze Morphology and Spatially Mapped Molecular Data Active
U24 2014
  • Martin Morgan
  • Roswell Park Cancer Institute
Cancer Genomics: Integrative and Scalable Solutions in R / Bioconductor Active
U24 2014
  • Guergana Savova
  • Boston Children's Hospital
  • University of Pittsburgh
Cancer Deep Phenotyping Extraction from Electronic Medical Records Active
U24 2014
  • Trey Ideker
  • University of California, San Diego
NDEx - the Network Data Exchange, A Network Commons for Biologists Active
R01 2014
  • Laura Rozek
  • Maureen Sartor
  • University of Michigan
Integrative Epigenomic/Genomic Profiling and Biomarker Discovery in HPV+ and HPV- Complete
U01 2014
  • Guoqian Jiang
  • Mayo Clinic - Rochester, Minnesota
caCDE-QA: A Quality Assurance Platform for Cancer Study Common Data Elements Complete
U01 2014
  • Hong Yu
  • University of Massachusetts Medical School
EMR Adverse Drug Event Detection for Pharmacovigilance Complete
U01 2014
  • Jingshan Huang
  • University of South Alabama
OmniSearch: A Semantic Search Tool for Discovering MicroRNAs' Critical Roles in Human Cancer Complete
U01 2014
  • Benjamin Berman
  • Cedars-Sinai Medical Center
Software Tools For Regulatory Analysis of Large Cancer Methylome Datasets Complete
U01 2014
  • Bobbie-Jo Mary Webb-Robertson
  • Pacific Northwest National Laboratory
Interactive Informatics Resource for Research-driven Cancer Proteomics Complete
U01 2013
  • Rachel Karchin
  • Johns Hopkins University
Informatics Tools for High-Throughput Analysis of Cancer Mutations Complete
U01 2013
  • Elmer Bernstam
  • Funda Meric-Bernstam
  • University of Texas MD Anderson Cancer Center
  • University of Texas Health Sci. Center, Houston
Informatics to Enable Routine Personalized Cancer Therapy Complete
U24 2013
  • Michael Becich
  • University of Pittsburgh
Advanced Development of TIES-Enhancing Access to Tissue for Cancer Research Complete
U24 2013
  • David Haussler
  • University of California, Santa Cruz
Cloud Based Resource for Data Hosting, Visualization and Analysis Using UCSC Cancer Genomics Browser Complete
U24 2013
  • Aviv Regev
  • Broad Institute
Trinity: Transcriptome Assembly for Genetic and Functional Analysis of Cancer Active
R01 2013
  • Joshua Stuart
  • University of California, Santa Cruz
ESCE: Discovering Molecular Processes Complete
U24 2013
  • Ron Kikinis
  • Andrey Fedorov
  • Brigham and Women's Hospital
  • Harvard Medical School
Quantitative Image Informatics for Cancer Research (QIICR) Complete
R01 2013
  • Hiroyuki Yoshida
  • Massachusetts General Hospital
Cloud-Computer-Aided Diagnostic Imaging Decision Support System Complete
R01 2013
  • William Noble
  • University of Washington
Interpreting Massive Genomic Data Sets via Summarization Complete
U01 2013
  • Shirley Liu
  • Dana-Farber Cancer Institute
Developing Informatics Technologies to Model Cancer Complete
U01 2011
  • John Quackenbush
  • Dana-Farber Cancer Institute
MeV: Software for Next Generation Genomic Data Analysis Complete
R01 2002
  • Janan Eppig
  • Carol Bult
  • Jackson Laboratory
Electronic Access to Mouse Tumor Data Complete