Frequently Asked Questions

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Can the generation of new (primary) data be supported through any of these mechanisms?
In general, the scope of work should be limited to informatics technology development. However, small scale, validation studies may be proposed.
How is the Special Emphasis Panel (SEP) reviewing proposals selected? At what point after submission of my proposal can I learn who is on the panel?
SEP members are selected based on the topic areas represented for each round of applications received. The tentative roster is available here at approximately 6-8 weeks after the receipt date.
Can you provide examples of the kinds of technologies this initiative is interested in supporting?
Listed below are some examples that are relevant to all four funding mechanisms of the ITCR Program.
- experiment design and execution
- data collection
- data processing and analysis
- data quality assessment
- data integration
- data presentation and visualization
- text mining and natural language processing
- data compression, storage, organization, transmission
In addition, please refer to the Specific Research Objectives in Section I of the Funding Opportunity Announcements for additional examples specific to each mechanism. These are not exhaustive lists; other informatics technologies might also be of interest to NCI. Please refer to the Program Contact listed on this website to discuss.
I intend to apply to the Sustainment U24 and will be proposig a budget greater than $500,000 direct costs in any year. Do I need to submit an Awaiting Receipt of Applications (ARA)?
ARA is not required when the application is in response to an RFAs which has a specific set-aside and expected funding levels as is the case with RFA-CA-20-010.
Which announcement should I choose?
Choose the (R21) if you are a computational scientist and want to develop a novel algorithm or method with the potential for significant value to cancer research.

Choose the (U01) if you are a computational scientist and want to collaborate with multiple cancer researchers in the development of new informatics technologies for cancer research.

Choose the (U24) if you are a computational scientist and want to further develop an existing informatics technology for enhanced functionality and utility and for broader impact in cancer research.

Choose the (U24) if you have developed an informatics technology resource has made a demonstrated impact on cancer research and require support to sustain this resource.
Do I have to get an R21 award under ITCR before I can apply for a U01 award, or a U01 before I can apply for a U24?
No, your existing technology does not have to be supported by NCI to apply for any of the U awards.
I am an NIH intramural scientist. Am I eligible to apply?
NIH intramural investigators are eligible to apply as co-investigators or collaborators without funds requested for their components.
Can for-profit entities apply for funding through this Initiative?
Commercial organizations, including small businesses with strong capabilities in informatics research and development, can submit proposals in response to the program's funding opportunity announcements. Public-private collaboration in informatics technology development and dissemination is encouraged.
Are foreign institutions eligible to apply?
Yes, foreign institutions may apply to all of the mechanisms.
Regarding the Software Dissemination Plan, do I have to share source code developed previously with other sources of funding?
No. Only code developed with ITCR support is expected to be released as described in the funding announcement.
What is the page limit for applications responding to the ITCR RFA?
The Research Strategy section is limited to 6 pages for the R21 RFA and 12 pages for the U01 and U24 RFAs.
What are the NCI Divisions involved in the ITCR program?
ITCR is a trans-NCI program with all four extramural divisions participating in the program: Division of Cancer Biology (DCB), Division of Cancer Control and Population Science (DCCPS), Division of Cancer Prevention (DCP), Division of Cancer Treatment and Diagnosis (DCTD). Center for Biomedical Informatics and Information Technology (CBIIT) is coordinating program activities across the divisions.
I still have other questions that are not answered here. Whom should I contact?
Please contact Juli Klemm.
Is there a minimal Level of Effort PIs must have on ITCR grants?
Yes, please refer to the guidelines stated in each RFAs.

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