Cancer is a complex disease system involving multiple molecular, genetic, and cellular events. From its early initiation through progression and metastasis, cancer can adapt and evolve as a result of both internal and external signals. These properties make cancer difficult to predict, prevent, and treat. There has been significant progress in characterizing the genetics of cancer, as well as the downstream effects on the molecular and cellular pathways that are critical for the initiation and progression of cancer. However, studies focused on the role of one gene have highlighted the need to understand cancers as integrated systems of genes, networks, and intercellular interactions.
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- Deprecated function: Optional parameter $checkbox declared before required parameter $input is implicitly treated as a required parameter in include_once() (line 1442 of /local/drupal/itcr/includes/bootstrap.inc).
- Deprecated function: Optional parameter $key declared before required parameter $is_multi is implicitly treated as a required parameter in require_once() (line 342 of /local/drupal/itcr/includes/module.inc).
- Deprecated function: Optional parameter $route declared before required parameter $is_multi is implicitly treated as a required parameter in require_once() (line 342 of /local/drupal/itcr/includes/module.inc).
- Deprecated function: Return type of crumbs_PluginSystem_PluginMethodIterator::current() should either be compatible with Iterator::current(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 4 of /local/drupal/itcr/sites/all/modules/crumbs/lib/PluginSystem/PluginMethodIterator.php).
- Deprecated function: Return type of crumbs_PluginSystem_PluginMethodIterator::next() should either be compatible with Iterator::next(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 4 of /local/drupal/itcr/sites/all/modules/crumbs/lib/PluginSystem/PluginMethodIterator.php).
- Deprecated function: Return type of crumbs_PluginSystem_PluginMethodIterator::key() should either be compatible with Iterator::key(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 4 of /local/drupal/itcr/sites/all/modules/crumbs/lib/PluginSystem/PluginMethodIterator.php).
- Deprecated function: Return type of crumbs_PluginSystem_PluginMethodIterator::valid() should either be compatible with Iterator::valid(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 4 of /local/drupal/itcr/sites/all/modules/crumbs/lib/PluginSystem/PluginMethodIterator.php).
- Deprecated function: Return type of crumbs_PluginSystem_PluginMethodIterator::rewind() should either be compatible with Iterator::rewind(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 4 of /local/drupal/itcr/sites/all/modules/crumbs/lib/PluginSystem/PluginMethodIterator.php).